Related Experiment Video
Updated: Jun 19, 2026
12:44
The In ovo CAM-assay as a Xenograft Model for Sarcoma
Published on: July 17, 2013
Angiosarcoma of the scalp.
Manjiri Das Gupta1, Nilay Chakrabarti, Pravin Agrawal
1Department of Surgery, K.J. Somaiya Medical College and Hospital, Sion, Mumbai - 400 022, India.
Summary
Angiosarcoma, a rare scalp tumor, was diagnosed in a 55-year-old female. Surgical excision and reconstruction led to no recurrence for two years, highlighting effective treatment for this vascular cancer.
Area of Science:
- Oncology
- Dermatology
- Surgical Pathology
Background:
- Angiosarcoma is a rare vascular soft tissue tumor often affecting the elderly, typically on the head and neck, particularly the scalp.
- Presentation varies from plaques to nodules, necessitating tailored treatment based on disease extent.
- Standard treatments include wide excision, radiotherapy, and chemotherapy for advanced or recurrent cases.
Observation:
- A 55-year-old female presented with a bleeding scalp lesion initially misdiagnosed as pyogenic granuloma.
- Excisional biopsy confirmed angiosarcoma with microscopic margin involvement.
- The patient underwent wide excision and reconstruction with a local rotation flap.
Findings:
- The patient received no adjuvant radiotherapy or chemotherapy post-surgery.
- No recurrence of the angiosarcoma was observed for two years following treatment.
- This case demonstrates successful management of a challenging scalp angiosarcoma.
Implications:
- Aggressive surgical management can be effective for scalp angiosarcoma, even with initial diagnostic challenges.
- Minimally invasive or conservative approaches may be viable in select cases, avoiding adjuvant therapies.
- Further research into optimal treatment strategies for localized angiosarcoma is warranted.
Related Concept Videos
01:26Arteries of the Head and Neck
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
01:19Veins of Head and Neck
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
01:30Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...