Related Experiment Video
Updated: Jun 19, 2026

06:06
Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
Knee joint arthroplasty after tibial osteotomy
Luca Amendola1, Matteo Fosco, Elisabetta Cenni
1VII Department of Orthopaedic Surgery, Rizzoli Orthopaedic Institute, University of Bologna, Bologna, Italy. luca.amendola@yahoo.it
International Orthopaedics
|November 3, 2009
Summary
Total knee arthroplasty (TKA) after high tibial osteotomy (HTO) shows high success rates. This study compared TKA in patients with prior HTO to primary TKA, finding comparable satisfactory outcomes for both groups.
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
Background:
- Medial compartment osteoarthritis often necessitates surgical intervention.
- High tibial osteotomy (HTO) is a common procedure for knee osteoarthritis.
- Total knee arthroplasty (TKA) is a definitive treatment for advanced knee arthritis.
Purpose of the Study:
- To compare the outcomes of TKA in patients with a history of HTO versus primary TKA.
- To evaluate the long-term efficacy and safety of TKA following HTO.
Main Methods:
- Retrospective comparison of 29 TKAs in patients with prior HTO to 29 primary TKAs.
- Follow-up duration averaged 97 months.
- Outcomes assessed based on patient satisfaction and revision rates.
Main Results:
- 96.5% of TKA cases in the HTO group reported satisfactory results.
- One patient in the HTO group required revision surgery due to implant loosening.
- Three patients in the HTO group underwent secondary patella resurfacing for pain.
- The control group (primary TKA) reported similar satisfactory results.
Conclusions:
- TKA following HTO demonstrates favorable and comparable outcomes to primary TKA.
- While revision and secondary procedures may be necessary, TKA remains a successful option for patients with prior HTO.
- This suggests that previous HTO does not significantly compromise TKA results.