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EpiLASIK with mitomycin C.

Christoph Winkler von Mohrenfels¹, Ramin Khoramnia, Mathias Maier

¹Augenklinik, Klinikum rechts der Isar, Technische Universität München, München, Germany. christoph.wvm@web.de

European Journal of Ophthalmology

|November 3, 2009

Summary

EpiLASIK with mitomycin C is a safe and effective procedure for higher myopia corrections, resulting in minimal haze and good visual outcomes. This treatment helps reduce haze and regression after laser eye surgery.

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Area of Science:

Ophthalmology
Refractive Surgery
Corneal Surgery

Background:

Photorefractive keratectomy (PRK) often uses mitomycin C to prevent haze and regression in high myopia.
EpiLASIK is an advanced surface ablation technique.

Purpose of the Study:

To evaluate the safety, stability, and efficacy of EpiLASIK combined with mitomycin C.
To assess outcomes for patients with higher intended refractive corrections.

Main Methods:

Fifty eyes of 29 patients underwent EpiLASIK using the Gebauer EpiLift microkeratome.
Mitomycin C (0.02%) was applied for 30 seconds post-ablation.
Ophthalmic examinations were conducted preoperatively and at 1, 3, 6, and 12 months post-surgery.

Main Results:

Twelve months post-surgery, 82% of eyes achieved within +/-0.5 D of intended correction.
86% of patients achieved uncorrected visual acuity of 1.0 or better.
Only 10% of patients showed trace haze, with most corneas remaining clear.

Conclusions:

EpiLASIK with mitomycin C is a safe and effective procedure for correcting higher myopia.
The use of mitomycin C minimizes corneal haze development.
The procedure demonstrates good visual stability and efficacy.