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EpiLASIK with mitomycin C

Christoph Winkler von Mohrenfels1, Ramin Khoramnia, Mathias Maier

  • 1Augenklinik, Klinikum rechts der Isar, Technische Universität München, München, Germany. christoph.wvm@web.de

European Journal of Ophthalmology
|November 3, 2009
PubMed
Abstract

Insights

EpiLASIK with mitomycin C is a safe and effective procedure for higher myopia corrections, resulting in minimal haze and good visual outcomes. This treatment helps reduce haze and regression after laser eye surgery.

Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Corneal Surgery

Background:

  • Photorefractive keratectomy (PRK) often uses mitomycin C to prevent haze and regression in high myopia.
  • EpiLASIK is an advanced surface ablation technique.

Purpose of the Study:

  • To evaluate the safety, stability, and efficacy of EpiLASIK combined with mitomycin C.
  • To assess outcomes for patients with higher intended refractive corrections.

Main Methods:

  • Fifty eyes of 29 patients underwent EpiLASIK using the Gebauer EpiLift microkeratome.
  • Mitomycin C (0.02%) was applied for 30 seconds post-ablation.
  • Ophthalmic examinations were conducted preoperatively and at 1, 3, 6, and 12 months post-surgery.

Main Results:

  • Twelve months post-surgery, 82% of eyes achieved within +/-0.5 D of intended correction.
  • 86% of patients achieved uncorrected visual acuity of 1.0 or better.
  • Only 10% of patients showed trace haze, with most corneas remaining clear.

Conclusions:

  • EpiLASIK with mitomycin C is a safe and effective procedure for correcting higher myopia.
  • The use of mitomycin C minimizes corneal haze development.
  • The procedure demonstrates good visual stability and efficacy.

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