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Improved prognosis for localized malignant lymphomas of the head and neck
Kasper Aanaes1, Elisabeth Kristensen, Elisabeth M Ralfkiaer
1Department of Otolaryngology-Head & Neck Surgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. kasperaanaes@hotmail.com
Conclusion:
In this study we found localized malignant lymphomas of the head and neck to be highly treatable and to have a significantly improved prognosis with recent treatment methods. The head and neck surgeon should keep in mind that the prognosis, especially for diffuse large B-cell lymphoma, has improved if the patient receives the optimal treatment.
Objectives:
The purpose of this study was to ascertain the current prognosis of localized malignant lymphoma of the head and neck given recent advancements in treatment and diagnostic features, as well as adding histological subtypes to the literature according to the 2001 classification.
Methods:
We present a retrospective study including a cohort of 100 consecutive patients who had localized malignant lymphoma within the head and neck region diagnosed at a single centre from 2000 to 2007.
Results:
The histology was revised according to the WHO classification and showed 58% with diffuse large B-cell lymphoma. The estimated 5-year overall survival rate was 83%, which should be seen in contrast to survival rates of 40-70% 25 years ago.
