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Effect of topical 1% tropicamide on Schirmer tear test results in clinically normal horses
Masoud Selk Ghaffari1, Amin Sabzevari, Behrad Radmehr
1Department of Clinical Studies, School of Veterinary Medicine, Islamic Azad University-Karaj Branch, Karaj, Iran. selkghaffari@gmail.com
Objective:
To observe the effect of topical 1% tropicamide on equine tear production as measured by Schirmer I tear test.
Materials And Methods:
Fourteen adult horses received one drop of 1% tropicamide ophthalmic solution in one eye and the opposite eye served as the control. The tear production in both eyes was tested at 1, 2, 4, 6, and 24 h after 1% tropicamide administration.
Results:
Measurements made 1 h after treatment revealed a significant reduction in Schirmer tear test values in tropicamide treated eyes (P = 0.002). The observed decrease in tear production was maintained up to 4 h after treatment (P = 0.002). Although tropicamide-induced decrease in STT values was observed in the treated eyes, the contralateral eyes did not show significant changes in Schirmer tear test results.
Conclusion:
Single dose of topical 1% tropicamide resulted in statistically significant reduction in Schirmer tear test values in clinically normal horses.
