Related Experiment Videos
Effect of phenytoin on plasma clozapine concentrations in two patients
1Department of Psychiatry, College of Medicine, University of Iowa, Iowa City 52242.
The Journal of Clinical Psychiatry
|January 1, 1991
Abstract:
Little is known about interactions of other drugs with the recently marketed antipsychotic clozapine. Two cases in which the addition of phenytoin caused a decrease in plasma clozapine concentrations and worsening of psychoses are described, and possible explanations are discussed.