Related Experiment Video
Updated: Jun 19, 2026

Planar Gradient Diffusion System to Investigate Chemotaxis in a 3D Collagen Matrix
Published on: June 12, 2015
Synchrony in reaction-diffusion models of morphogenesis: applications to curvature-dependent proliferation and
Lamia Abbas1, Jacques Demongeot, Nicolas Glade
1Institut National des Sciences Appliquées Rouen, Laboratoire de Mathématiques de l'INSA EA 3226, Place Emile Blondel BP 08, 76131 Mont-Saint-Aignan, France.
Abstract:
The paper presents the classical age-dependent approach of the morphogenesis in the framework of the von Foerster equation, in which we introduce a new constraint and study a new feature: (i) the new constraint concerns cell proliferation along the contour lines of the cell density, depending on the local curvature such as it favours the amplification of the concavities (like in the gastrulation process) and (ii) the new feature consists of considering, on the cell density surface, a remarkable line (the null mean Gaussian curvature line), on which the normal diffusion vanishes, favouring local coexistence of diffusing morphogens, metabolites or cells, and hence the auto-assemblages of these entities. Two applications to biological multi-agents systems are studied, gastrulation and feather morphogenesis.
Related Concept Videos
Actin Polymerization and Cell Motility
Actin cytoskeleton dynamics can produce pushing, pulling, and resistance forces that help the cell to migrate.
Morphogenesis
Cytoskeletal Coordination in Cell Migration
Partial Differential Equations
Modeling with Differential Equations
Mechanism of Lamellipodia Formation

