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Updated: Jun 19, 2026
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Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
Published on: January 29, 2016
Resistance training improves muscle strength and functional capacity in multiple sclerosis
U Dalgas1, E Stenager, J Jakobsen
1Department of Sport Science, University of Aarhus, Dalgas Ave. 4, 8000 Aarhus C, Denmark. dalgas@sport.au.dk
Neurology
|November 4, 2009
Summary
Progressive resistance training (PRT) significantly enhances muscle strength and functional capacity in multiple sclerosis (MS) patients. These gains are maintained for at least 12 weeks after the intervention, demonstrating long-term benefits for individuals with MS.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Exercise Science
Background:
- Multiple Sclerosis (MS) is a chronic neurological disease affecting muscle strength and functional capacity.
- Progressive Resistance Training (PRT) is a potential therapeutic intervention for MS-related impairments.
Purpose of the Study:
- To evaluate the efficacy of lower extremity PRT in improving muscle strength and functional capacity in MS patients.
- To determine if these improvements are sustained post-intervention.
Main Methods:
- A 12-week randomized controlled trial with 38 moderately impaired MS patients.
- Two arms: PRT exercise group and a control group.
- Measurements included knee extensor (KE) isometric strength and functional capacity (FS) at baseline, 12 weeks, and 24 weeks.
Main Results:
- The PRT group showed significant improvements in KE MVC (15.7%) and FS (21.5%) after 12 weeks (p < 0.05).
- These improvements were maintained at the 24-week follow-up.
- The control group also improved when they completed the PRT intervention post-study.
Conclusions:
- Twelve weeks of lower extremity PRT effectively improves muscle strength and functional capacity in MS patients.
- The benefits of PRT are durable, persisting after a 12-week period of self-guided activity.
- PRT is a viable strategy for managing functional decline in multiple sclerosis.
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