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Updated: Jun 19, 2026

Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
Published on: December 16, 2019
Reductive dearomatization of a substituted benzene triggered by a strong oxidant
1Davenport Chemical Research Laboratories, Department of Chemistry, University of Toronto, 80 St. George Street, Ontario, Canada.
Abstract:
Two new dinuclear platinum complexes Pt(2)Ph(4)L(Et) (1a) and Pt(2)Ph(4)L(F) (1b) (where L(Et) is 1,2,4,5-tetrakis(6-ethylquinolin-8-yl)benzene and L(F) is 1,2,4,5-tetrakis(6-trifluoromethoxylquinolin-8-yl)benzene) were synthesized and characterized. Triggered by an oxidant NCS, 1a and 1b displayed interesting reactivity of reductive dearomatization of the central phenyl rings of L(Et) and L(F) ligands respectively. The preliminary radical scavenger test gave some mechanistic insights.
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