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Updated: Jun 19, 2026

Direct Drug Delivery to Kidney via the Renal Artery
Published on: April 17, 2021
Embolization with absolute ethanol injection of insufficiently ligated renal artery after open nephrectomy
Biljana Markovic1, Zeljko Markovic, Tomislav Pejcic
1Department of Radiology, University of Belgrade Medical Faculty, Belgrade, Serbia. bimar@verat.net
Abstract:
A 54-year-old woman was admitted to hospital for hypotension and anemia which was due to intermittent hemorrhage from a lumbar drain. She had undergone open nephrectomy ten days earlier in another hospital for the right dysfunctional kidney with staghorn calculi. Ultrasound in our hospital showed a right retroperitoneal hematoma. Surgical exploration was performed twice whereby the hematoma was partially eliminated; however, the point of bleeding was not identified. Repeated attacks of bleeding from the drain accompanied by acute pain made the hypotension with tachycardia even worse, which led to a life-threatening hemorrhagic shock. Extravasation from the insufficiently ligated right renal artery was then shown on computed tomography aortography. After selective catheterization of this arterial stump with a mixture of alcohol and contrast media, complete occlusion of the remaining part of the resected renal artery was achieved. Application of absolute alcohol, though risky, proved to be a quick and efficient alternative method of occlusion of the bleeding renal arterial stump.

