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Effects of aerobic exercise training on visceral fat and serum adiponectin concentration in ovariectomized rats
A Damirchi1, R Mehdizade, M M Ansar
1Department of Physical Education, Guilan University of Medical Sciences, Rasht, Iran.
Objective:
The aim of this experimental study was to investigate the effects of exercise training on visceral fat and adiponectin levels in ovariectomized (OVX) rats.
Method:
Female Wistar rats were divided into OVX (n = 20) and sham-operated control (SHAM; n = 8) groups. OVX rats were subdivided into a sedentary (OVX-SED; n = 10) and an exercise (OVX-EX; n = 10) group. The exercise consisted of 8 weeks of aerobic exercise (26 m/min, 5 days/week, 60 min/day, 10% slope).
Results:
In OVX rats, body weight was 21% greater (255.2 +/- 9.31 vs. 211.63 +/- 3.23; p < 0.01) and visceral fat was 29% greater (10.87 +/- 0.66 vs. 8.43 +/- 0.45; p < 0.05) than in SHAM rats. After training, visceral fat was 20% lower in OVX-EX rats than in OVX-SED rats (8.72 +/- 0.46 vs. 10.87 +/- 0.66; p < 0.05). After 8 weeks of running on the treadmill, levels of serum glucose, insulin and serum adiponectin, and the homeostasis model assessment of insulin resistance were not changed significantly in the OVX-EX group.
Conclusion:
These results suggest that 8-week exercise training induces a decrease in visceral fat, and this reduction without weight loss does not change serum adiponectin levels and insulin sensitivity in ovariectomized rats.
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