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Related Experiment Videos

Common variable immunodeficiency: the disorder and treatment.

M W Yocum1, J M Kelso

  • 1Division of Allergic Diseases and Internal Medicine, Mayo Clinic, Rochester, MN 55905.

Mayo Clinic Proceedings
|January 1, 1991
PubMed
Summary

Common variable immunodeficiency (CVID) is a rare disorder characterized by low immunoglobulin levels and recurrent infections. This case highlights complications like anti-IgA antibodies and anaphylaxis, emphasizing gamma-globulin therapy.

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Area of Science:

  • Immunology
  • Clinical Medicine
  • Rare Diseases

Background:

  • Common variable immunodeficiency (CVID) is a heterogeneous group of disorders characterized by low immunoglobulin levels, impaired antibody production, and recurrent bacterial infections.
  • Patients with CVID often require lifelong immunoglobulin replacement therapy.
  • This case presents a patient with CVID complicated by anti-IgA antibodies and a history of anaphylaxis to gamma-globulin.