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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Dual-source CT coronary angiography without heart rate or rhythm control in comparison with conventional coronary
Xiang Ming Fang1, Hong Wei Chen, Xiao Yun Hu
1Department of Radiology, Wuxi People's Hospital, Nanjing Medical University, 214023, Wuxi City, Jiangsu Province, China.
Insights
Dual-source CT angiography (DSCTA) accurately diagnoses coronary artery stenosis (CAS) even without heart rate control. This imaging technique shows high reliability and can serve as a primary tool for detecting CAS, potentially replacing conventional coronary angiography.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Diagnostic Technology
Background:
- Coronary artery stenosis (CAS) diagnosis often requires heart rate control during imaging.
- Dual-source CT angiography (DSCTA) offers potential for rapid cardiac imaging.
- Evaluating DSCTA's efficacy without heart rate control is crucial for clinical application.
Purpose of the Study:
- To assess the diagnostic value and accuracy of DSCTA in identifying coronary artery stenosis (CAS).
- To evaluate DSCTA performance in patients with uncontrolled heart rates or rhythms.
- To compare DSCTA findings with conventional coronary angiography (CCA) as the gold standard.
Main Methods:
- Eighty-nine patients with varying heart rates/rhythms underwent both DSCTA and CCA within a week.
- Diagnostic quality of coronary segments was analyzed for both modalities.
- Kappa test assessed intermodality agreement for CAS grading; CCA served as the gold standard.
Main Results:
- DSCTA achieved a high evaluable rate (98.8%) for coronary arteries, irrespective of heart rate.
- Sensitivity and specificity for detecting CAS were 97.9% and 96.8%, respectively.
- Excellent intermodality agreement (k=0.856) was observed between DSCTA and CCA in grading CAS.
Conclusions:
- DSCTA is a highly accurate and reliable tool for evaluating CAS, even without heart rate control.
- The technique demonstrates significant potential as a primary diagnostic tool for CAS.
- DSCTA may serve as a viable alternative to conventional coronary angiography in selected patient groups.
Abstract:
To explore the value of dual-source CT angiography (DSCTA) in diagnosing coronary artery stenosis (CAS) without heart rate or rhythm control. Eighty-nine patients with different heart rates/rhythms underwent both DSCTA and conventional coronary angiography (CCA) in 1 week. The diagnostic quality of normal coronary arteries and stenosed segments using DSCTA and CCA were analyzed, respectively, with CCA as the gold standard. Kappa test was used to assess the intermodality agreement between DSCTA and CCA in grading CAS. The value of DSCTA in diagnosing CAS (> 50% stenoses) were analyzed as well. The total evaluable rate of DSCTA in detecting coronary arteries was 98.8%. No significant difference between evaluable rates from different groups of heart rate (chi(2) = 1.745, P > 0.05) was found. Sensitivity, specificity, positive and negative predictive values of DSCTA in detecting CAS and > 50% stenoses were 97.9, 96.8, 89.5, 99.4 and 97.2, 95.5, 80.3, 99.4%, respectively; The inter-modality agreement between DSCTA and CCA in grading CAS was found to be excellent (k = 0.856, P < 0.01). DSCTA provides high accuracy and reliability for evaluation of CAS in a high suspected patient group without heart rate/rhythm control. It can be used as a powerful primary tool for the detection of CAS and a potential substitute of CCA.
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