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Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...

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Preparation of Keratin Hydrolysate from Chicken Feathers and Its Application in Cosmetics
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Compounding dermatologic preparations in developing countries.

Diane Lamarre1, Marie-Eve Bertrand, Denis Giroux

  • 1Faculty of Pharmacy, University of Montreal, Pharmacists without borders, Canada. lamarrerenaud@sympatico.ca

Dermatologic Therapy
|November 6, 2009
PubMed
Summary

This study highlights the importance of accessible dermatologic medications in developing nations. A collaborative effort successfully established a sustainable drug preparation program for common skin conditions in Haiti.

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Area of Science:

  • Dermatology
  • Pharmacology
  • Global Health

Background:

  • Access to essential medications is critical in developing countries.
  • Dermatologic conditions are prevalent in tropical and equatorial regions.
  • Limited availability and high cost of treatments hinder patient care.

Purpose of the Study:

  • To develop a sustainable model for preparing and distributing essential dermatologic medications in resource-limited settings.
  • To address the unmet needs of common skin disorders in tropical areas.
  • To empower local healthcare staff through specialized training.

Main Methods:

  • An interdisciplinary team of dermatologists and pharmacists compiled a master list of essential dermatologic preparations.
  • A pilot project was implemented at Cardinal Leger Hospital in Leogane, Haiti.
  • Local hospital staff received comprehensive training on drug preparation and dispensing.

Main Results:

  • The pilot project successfully established a system for preparing and offering necessary dermatologic drugs.
  • The program provided medications at a reasonable price, improving accessibility for the local population.
  • The initiative demonstrated long-term sustainability, continuing four years after its inception.

Conclusions:

  • Interdisciplinary collaboration can effectively address medication access challenges in developing countries.
  • Training local healthcare professionals is key to sustainable drug supply systems.
  • The Haiti pilot project offers a replicable model for improving dermatologic care globally.