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Related Experiment Video

Updated: Jun 19, 2026

A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting

A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting

Published on: May 16, 2013

Thrombocytopenia in malaria.

Qurban Hussain Shaikh¹, Syed Masroor Ahmad, Amanullah Abbasi

¹Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi. bilalcohussain55@hotmail.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|November 6, 2009

Summary

Thrombocytopenia, a low platelet count, is common in malaria patients. Plasmodium vivax infections show a higher frequency of this condition compared to Plasmodium falciparum.

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Area of Science:

Hematology
Infectious Diseases
Parasitology

Background:

Thrombocytopenia is a frequent complication of malaria.
Understanding its prevalence in different Plasmodium species is crucial for patient management.

Purpose of the Study:

To determine the frequency of thrombocytopenia in patients with malarial parasites (MP).

Main Methods:

A cross-sectional study was conducted with 124 MP-positive patients.
Platelet counts were analyzed, defining thrombocytopenia as < 150,000/cmm.
Included infections with Plasmodium falciparum and Plasmodium vivax.

Main Results:

Thrombocytopenia was observed in 80.6% (100/124) of MP-positive patients.
Frequency was 71.87% in Plasmodium falciparum and 93.33% in Plasmodium vivax infections.
Plasmodium vivax infections showed a significantly higher rate of thrombocytopenia.

Conclusions:

Thrombocytopenia is a common hematological finding in malaria.
The condition is particularly prevalent in Plasmodium vivax infections.
This highlights the importance of monitoring platelet counts in malaria patients.