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Related Experiment Video

Updated: Jun 19, 2026

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease

Published on: October 14, 2021

Suicidal ideation in Parkinson's disease.

Arthur Kummer¹, Francisco Cardoso, Antonio Lucio Teixeira

¹Neuropsychiatric Branch of the Neurology Division, University Hospital, Federal University of Minas Gerais, Belo Horizonte, Brazil.

|November 6, 2009

Summary

Suicide attempts are rare in Parkinson's disease (PD) patients. However, suicidal ideation is elevated, particularly in younger patients with major depression, which is the primary predictor.

Related Experiment Videos

Last Updated: Jun 19, 2026

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease

Published on: October 14, 2021

Area of Science:

Neurology
Psychiatry
Epidemiology

Background:

Parkinson's disease (PD) is a neurodegenerative disorder.
Mental health comorbidities, including depression, are common in PD.
The prevalence of suicidal ideation and attempts in PD requires further investigation.

Purpose of the Study:

To determine the frequency of suicidal ideation and suicide attempts in non-demented Parkinson's disease patients.
To identify factors associated with suicidal ideation in this population.

Main Methods:

Utilized the Mini International Neuropsychiatric Interview (MINI), Beck Depression Inventory (BDI), and Hamilton Rating Scale for Depression (HAM-D) in 90 PD patients.
Conducted comprehensive neurologic and cognitive assessments.
Analyzed suicide risk data from MINI, BDI, and HAM-D.

Main Results:

No suicide attempts were reported among the 90 participants.
Suicidal ideation was present in 14.4% of PD patients, as per the MINI.
Suicidal ideation correlated with younger age, earlier PD onset, panic disorder, social anxiety disorder, and major depression. Major depression was the strongest predictor.

Conclusions:

Suicide attempts appear infrequent in Parkinson's disease.
Suicidal ideation is potentially elevated in PD patients.
Major depression is the most significant predictor of suicidal ideation in Parkinson's disease.