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Updated: Jun 19, 2026

Lexical Decision Task for Studying Written Word Recognition in Adults with and without Dementia or Mild Cognitive Impairment
Published on: June 25, 2019
Encoding processes influence word-stem completion priming in Alzheimer's disease: a meta-analysis.
Xavier Millet1, Melanie Le Goff, Jean Bouisson
1Inserm U897, Universite Victor Segalen Bordeaux 2, 33076 Bordeaux, France. Xavier.Millet@isped.u-bordeaux2.fr
Alzheimer's disease patients show word-stem completion priming, but it's reduced. Priming is preserved when patients actively generate words during encoding, unlike passive reading tasks.
Area of Science:
- Neuroscience
- Cognitive Psychology
Background:
- Controversy exists regarding word-stem completion priming in Alzheimer's disease (AD).
- Methodological variations, particularly encoding instructions, may explain differing results.
- Understanding implicit memory in AD is crucial for cognitive rehabilitation.
Purpose of the Study:
- To meta-analytically assess word-stem completion priming in AD.
- To investigate the influence of encoding instructions on priming effects in AD.
Main Methods:
- Meta-analysis of 678 Alzheimer's disease patients and 640 controls.
- Comparison of priming performance across different encoding conditions (reading, rating, semantic judgment, word generation).
Main Results:
- Overall, Alzheimer's disease patients exhibit significant word-stem completion priming, albeit reduced compared to controls.
- Priming was impaired under passive encoding (reading, rating).
- Priming was comparable to controls under active encoding (semantic judgment, word generation).
Conclusions:
- Word-stem completion priming is present but attenuated in Alzheimer's disease.
- Active word generation at encoding may help mitigate cognitive deficits and improve priming.
- Encoding task demands significantly modulate implicit memory performance in AD.
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