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Related Experiment Video

Updated: Jun 19, 2026

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI
07:31

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI

Published on: November 1, 2014

Equine immune-mediated keratopathies.

Andrew Matthews1, Brian C Gilger

  • 1McKenzie Bryson and Marshall, 21 Hill Street, Kilmarnock, UK.

Veterinary Ophthalmology
|November 7, 2009
PubMed
Summary

Equine immune-mediated keratitis (IMMK) is a common eye disease in horses. This review compares clinical signs, pathogenesis, and treatments for IMMK in horses.

Area of Science:

  • Veterinary Ophthalmology
  • Equine Internal Medicine

Background:

  • Equine immune-mediated keratitis (IMMK) is a prevalent condition affecting horses globally.
  • Understanding the clinical presentation and underlying mechanisms is crucial for effective management.

Purpose of the Study:

  • To compare the clinical differences of equine IMMK between affected horses.
  • To review current theories on the pathogenesis of equine IMMK.
  • To summarize and evaluate current treatment strategies for equine IMMK.

Main Methods:

  • Literature review of equine immune-mediated keratitis.
  • Comparative analysis of clinical presentations.
  • Synthesis of current research on pathogenesis and treatment.

Main Results:

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Murine Model of Epicutaneously-Induced Immunomodulation

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Last Updated: Jun 19, 2026

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI
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Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI

Published on: November 1, 2014

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
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Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

Published on: December 18, 2012

Murine Model of Epicutaneously-Induced Immunomodulation
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Murine Model of Epicutaneously-Induced Immunomodulation

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  • Clinical signs of equine IMMK can vary, necessitating accurate diagnosis.
  • Pathogenesis theories involve complex immune responses within the cornea.
  • Current treatments include medical and surgical options, with varying success rates.

Conclusions:

  • Equine IMMK requires a thorough understanding of its diverse clinical features.
  • Further research into pathogenesis may reveal novel therapeutic targets.
  • Tailored treatment approaches are essential for optimal outcomes in horses with IMMK.