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Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites
Published on: May 18, 2016
Fixed cutaneous sporotrichosis.
Matthew J Mahlberg1, Rishi Patel, Karla Rosenman
1Department of Dermatology, New York University, USA.
Dermatology Online Journal
|November 7, 2009
Summary
Sporotrichosis, a fungal infection, can present as a fixed skin form. Early diagnosis is crucial to prevent significant scarring and patient morbidity.
Area of Science:
- Mycology
- Dermatology
- Infectious Diseases
Background:
- Sporotrichosis is a subcutaneous fungal infection caused by Sporothrix schenckii.
- While lymphocutaneous is common, fixed cutaneous sporotrichosis also occurs.
- Clinical history, including travel and occupation, aids in suspecting this mycosis.
Observation:
- A case of fixed cutaneous sporotrichosis is presented.
- The patient experienced delayed diagnosis.
- This delay resulted in notable scarring and morbidity.
Findings:
- Histopathology and tissue culture are essential for confirming Sporothrix schenckii diagnosis.
- Multiple specimens may be required for definitive diagnosis.
- Fixed cutaneous sporotrichosis can lead to significant patient suffering if not promptly identified.
Implications:
- Highlights the importance of considering sporotrichosis in the differential diagnosis of cutaneous lesions.
- Emphasizes the need for timely diagnostic procedures to minimize patient morbidity.
- Underscores the potential for long-term cosmetic and functional impairment due to delayed treatment.
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