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Related Concept Videos

Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Muscles of the Pelvic Floor and Perineum01:26

Muscles of the Pelvic Floor and Perineum

The muscles of the pelvic floor and perineum are crucial for supporting the pelvic organs, controlling continence, and aiding in sexual function, childbirth, and core stability. They are typically divided into the superficial perineal layer and the deep pelvic floor layer.
Perineal Layer
The perineum is a diamond-shaped area below the pelvic diaphragm, divided into an anterior urogenital triangle that contains the external genitals and a posterior anal triangle housing the anus. The urogenital...
Uterine Tubes01:16

Uterine Tubes

The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Related Experiment Video

Updated: Jun 19, 2026

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
05:46

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Published on: January 17, 2019

Cutaneous piloleiomyomata.

Gideon Smith1, Noushin Heidary, Rishi Patel

  • 1Department of Dermatology, New York University, USA.

Dermatology Online Journal
|November 7, 2009
PubMed
Summary
This summary is machine-generated.

A man experienced painful, growing subcutaneous nodules diagnosed as piloleiomyoma. Current pain management offered limited relief, necessitating surgical intervention for the smooth muscle tumors.

Related Experiment Videos

Last Updated: Jun 19, 2026

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
05:46

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Published on: January 17, 2019

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Piloleiomyomas are benign tumors originating from smooth muscle cells.
  • These tumors can manifest as painful, subcutaneous nodules.

Observation:

  • A 49-year-old male presented with an 8-month history of progressively painful subcutaneous nodules.
  • The nodules increased in size, number, and pain intensity over time.

Findings:

  • Biopsy confirmed smooth muscle proliferation consistent with piloleiomyoma.
  • Tumor cells stained positive for actin, a smooth muscle marker.
  • Pharmacological treatments including gabapentin and nifedipine provided minimal pain relief.

Implications:

  • This case highlights the challenges in managing symptomatic piloleiomyomas.
  • Surgical excision may be a necessary treatment option for extensive or intractable cases.
  • Further research into effective non-surgical pain management for piloleiomyomas is warranted.