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Related Concept Videos

Structure and Organization of Smooth Muscles01:13

Structure and Organization of Smooth Muscles

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Smooth muscle tissue is a type of muscle tissue that can be found lining various vital organs in the human body, including the lungs, blood vessels, digestive tract, and respiratory tract. This type of tissue is responsible for regulating the movements of these organs, playing crucial roles in the functioning of various systems, including the vascular, digestive, respiratory, and urinary systems.
Structure of smooth muscle cell
Smooth muscle cells are spindle-shaped with tapering ends and a...
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Functions of Smooth Muscles01:23

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Smooth muscles are an important type of muscle tissue that plays a vital role in the involuntary movements of internal organs. For example, they help regulate the movement of food through the gut and the flow of blood through the circulatory system.
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Smooth Muscle Contraction01:25

Smooth Muscle Contraction

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Smooth muscle contraction is a complex process vital for various bodily functions, from maintaining blood vessel tension to facilitating the movement of food through the digestive tract. Unlike striated muscles, smooth muscle contraction begins more slowly and lasts longer.
The onset of contraction is triggered by an increase in calcium ions within the sarcoplasm, similar to the process in striated muscle. However, smooth muscles have a relatively smaller reservoir of the sarcoplasmic...
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Satellite Stem Cells and Muscular Dystrophy01:21

Satellite Stem Cells and Muscular Dystrophy

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Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
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Related Experiment Video

Updated: Feb 17, 2026

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
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Acquired smooth-muscle hamartoma.

Molly Yancovitz1, Mercedes E Gonzalez, Henry J Votava

  • 1Department of Dermatology, New York University, USA.

Dermatology Online Journal
|November 7, 2009
PubMed
Summary
This summary is machine-generated.

A rare smooth-muscle hamartoma, a benign skin tumor, was diagnosed in a 52-year-old woman. This uncommon condition, often present from birth, shares features with Becker nevi.

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Area of Science:

  • Dermatology
  • Pathology
  • Oncology

Background:

  • Cutaneous smooth-muscle hamartomas are uncommon benign neoplasms.
  • While most lesions are congenital, acquired cases have been reported.
  • These hamartomas are considered part of a spectrum of neoplasms that includes Becker nevi.

Observation:

  • A 52-year-old woman presented with a long-standing plaque on her left upper arm.
  • The plaque was characterized by hyperpigmentation, hypertrichosis, and induration, with occasional pruritus.
  • The lesion initially developed during childhood.

Findings:

  • Histopathologic examination confirmed the diagnosis of smooth-muscle hamartoma.
  • The observed clinical and histopathologic features align with those of smooth-muscle hamartomas.
  • The case highlights the shared characteristics between smooth-muscle hamartomas and Becker nevi.

Implications:

  • This case contributes to the understanding of smooth-muscle hamartomas, particularly acquired forms.
  • Recognizing the spectrum of smooth-muscle hamartomas and Becker nevi is crucial for accurate diagnosis.
  • Further research may elucidate the specificPathogenesis and classification of these related neoplasms.