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Updated: Jun 19, 2026

Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti
Published on: January 17, 2025
Strongyloides stercoralis and the immune response
Nnaemeka C Iriemenam1, Adekunle O Sanyaolu, Wellington A Oyibo
1Department of Medical Microbiology & Parasitology, College of Medicine of the University of Lagos, Idi-araba, PMB 12003 Lagos, Nigeria. iriemeka@yahoo.co.uk
Abstract:
The immune system is a highly evolved network of cells and molecules that can distinguish between invading pathogens and the body's own cells. But helminths, in their complex forms, are capable of down-regulating host immunity, protecting them from being eliminated and also minimizing severe pathology in the host. This review focuses on Strongyloides stercoralis and the immune responses in immunocompetent and/or immunocompromised individuals. It also highlights the implications for diagnosis/treatment and draws attention to an emerging public health disease. The solution to reducing the prevalence of strongyloidiasis remains on the effectiveness of pre-emptive measures in endemic communities, increased awareness, prompt early diagnosis as well as timely treatment.
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