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Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats
06:38

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Published on: October 13, 2018

[Delayed puberty].

T Edouard1, M Tauber

  • 1Unité d'endocrinologie pédiatrique, maladies osseuses, génétique et gynécologie médicale, hôpital des enfants de Purpan, CHU de Toulouse, TSA, 31059 Toulouse cedex 9, France. edouard.t@chu-toulouse.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|November 7, 2009
PubMed
Summary
This summary is machine-generated.

Delayed puberty, the absence of secondary sexual characteristics by age 13 in girls and 14 in boys, requires investigation for hypogonadism or constitutional delay. Treatment involves addressing the cause, hormonal therapy, and psychological support.

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Area of Science:

  • Pediatric Endocrinology
  • Reproductive Medicine
  • Human Growth and Development

Context:

  • Delayed puberty is a common clinical presentation in pediatric endocrinology.
  • Diagnosis involves differentiating between central/peripheral hypogonadism and constitutional delay.
  • Specific considerations exist for girls (Turner syndrome) and boys (constitutional delay).

Purpose:

  • To define delayed puberty in girls and boys.
  • To outline diagnostic pathways for hypogonadism and constitutional delay.
  • To discuss management strategies including hormonal replacement and psychological support.

Summary:

  • Delayed puberty is defined by the lack of breast development by age 13 in girls and testicular enlargement by age 14 in boys.
  • Investigations differentiate central/peripheral hypogonadism from constitutional delay, with Turner syndrome a key consideration in girls.
  • Treatment is etiological, incorporating hormonal replacement therapy (estrogen/testosterone) and psychological management.

Impact:

  • Provides a clear definition and diagnostic framework for delayed puberty.
  • Highlights the importance of early diagnosis and appropriate management for optimal outcomes.
  • Emphasizes the multidisciplinary approach required for effective treatment of delayed puberty.