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Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)
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The comprehensive microbial resource.

Tanja Davidsen1, Erin Beck, Anuradha Ganapathy

  • 1J Craig Venter Institute, Rockville, MD 20850, USA. tanjad@jcvi.org

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Summary
This summary is machine-generated.

The Comprehensive Microbial Resource (CMR) offers a centralized platform for exploring bacterial and archaeal genomes. It provides extensive tools and consistent annotation for advanced genomic data analysis and research.

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Area of Science:

  • Microbiology
  • Bioinformatics
  • Genomics

Background:

  • The Comprehensive Microbial Resource (CMR) is a web-based platform.
  • It centralizes sequence and annotation data for publicly available bacterial and archaeal genomes.

Purpose of the Study:

  • To provide a comprehensive resource for displaying, searching, and analyzing microbial genomic data.
  • To offer consistent, automated annotation and comparative analysis tools for effective genomic data mining.

Main Methods:

  • The CMR integrates original GenBank annotations with secondary automated structural and functional annotations.
  • It stores precomputed homology searches for genome comparisons.
  • The platform offers over 50 tools for data utilization across 571 genomes.

Main Results:

  • Users can access gene-level annotation and evidence.
  • Genome-level information includes graphical displays, pathway maps, and summary data.
  • Comparative tools facilitate analysis between genomes, including homology and alignment.

Conclusions:

  • The CMR facilitates genomic research and analysis through its extensive data and tools.
  • The platform's code and database are freely available for download.
  • The CMR is a valuable resource, cited in over 200 scientific publications.