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Related Concept Videos

Assessment of the Mouth01:26

Assessment of the Mouth

A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Introduction to Language of Pathophysiology ll01:17

Introduction to Language of Pathophysiology ll

This lesson explores key terms that describe how diseases progress, their outcomes, and their distribution in populations.Diagnostic tests identify diseases and monitor treatment. These include blood and urine tests, biopsies, imaging (X-ray, MRI), and detection of infectious agents.Remission is a reduction or disappearance of symptoms.Exacerbation refers to the worsening of symptoms, such as increased wheezing during an asthma attack.A precipitating factor triggers an acute episode, while a...

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Updated: Jun 18, 2026

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
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Published on: March 1, 2024

Oral lichen planus: a review.

M Carrozzo1, R Thorpe

  • 1Oral Medicine, School of Medical Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, UK. marco.carrozzo@ncl.ac.uk

Minerva Stomatologica
|November 7, 2009
PubMed
Summary

Oral lichen planus (OLP) is a chronic inflammatory condition. While generally low risk for malignancy, its management requires symptom control, and long-term effects of treatments like corticosteroids need further study.

Area of Science:

  • Immunology
  • Dermatology
  • Oral Medicine

Background:

  • Oral lichen planus (OLP) is a prevalent chronic inflammatory condition.
  • A genetic predisposition involving Th1 cytokine polymorphisms may underlie OLP pathogenesis.
  • Etiologic factors such as amalgam restorations and hepatitis C virus are under investigation.

Purpose of the Study:

  • To review the current understanding of oral lichen planus.
  • To discuss diagnostic criteria and management strategies.
  • To highlight areas needing further research, particularly regarding long-term treatment effects.

Main Methods:

  • Literature review of OLP pathogenesis, diagnosis, and treatment.
  • Analysis of genetic and environmental factors.

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  • Evaluation of current therapeutic approaches and their limitations.

    • Main Results:

    • OLP is characterized by T cell-mediated immune responses.
    • Diagnosis relies on clinical presentation, often confirmed by biopsy to rule out dysplasia and malignancy.
    • Topical immunomodulators like corticosteroids and calcineurin inhibitors are primary treatments.

    Conclusions:

    • While OLP has a low associated malignancy risk, definitive diagnosis and management are crucial.
    • Long-term safety and efficacy data for current OLP therapies are insufficient.
    • Further research is needed to establish optimal treatment guidelines for OLP.