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Origami Inspired Self-assembly of Patterned and Reconfigurable Particles
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Self-assembly of soft nanoparticles with tunable patchiness.

Thomas M Hermans1, Maarten A C Broeren, Nikos Gomopoulos

  • 1Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, The Netherlands.

Nature Nanotechnology
|November 7, 2009
PubMed
Summary

Researchers synthesized 6-nm nanoparticles with dynamic hydrophobic patches, enabling reversible self-assembly into complex structures in water. Dilution increases the topological connectivity of these nanoparticle assemblies, controlled by guest-host supramolecular chemistry.

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Area of Science:

  • Supramolecular Chemistry
  • Materials Science
  • Nanotechnology

Background:

  • Nanoparticle interactions dictate self-assembly into larger structures.
  • Directed interactions enable concepts like patchy colloids and colloidal molecules.
  • Surface patches on nanoparticles predict complex assembly modes.

Purpose of the Study:

  • To synthesize nanoparticles with dynamic hydrophobic patches.
  • To investigate their self-assembly behavior in aqueous solution.
  • To explore the role of guest-host supramolecular chemistry in ordering.

Main Methods:

  • Synthesis of 6-nm nanoparticles featuring dynamic hydrophobic patches.
  • Utilizing guest-host supramolecular chemistry with dendrimer hosts and hydrophilic guests.

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Nanosponge Tunability in Size and Crosslinking Density
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Last Updated: Jun 18, 2026

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles
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Grafting Multiwalled Carbon Nanotubes with Polystyrene to Enable Self-Assembly and Anisotropic Patchiness
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  • Observation of self-assembled structures in aqueous solution under varying concentrations.

    • Main Results:

    • Achieved reversible self-assembly of nanoparticles in aqueous solution.
    • Demonstrated that dilution leads to increased topological connectivity of assemblies.
    • Showcased control over mesoscopic ordering via hierarchical composition and concentration.

    Conclusions:

    • Dynamic hydrophobic patches on nanoparticles facilitate tunable self-assembly.
    • Guest-host interactions provide a mechanism for controlled nanoparticle organization.
    • Hierarchical composition and concentration are critical factors in mesoscopic ordering.