Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Regulation of Stroke Volume01:27

Regulation of Stroke Volume

The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Cardiac Output II: Effect of Stroke Volume on Cardiac Output01:22

Cardiac Output II: Effect of Stroke Volume on Cardiac Output

Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnosis and Management of Patent Foramen Ovale for Stroke Prevention: An Australian and New Zealand Consensus Statement Developed by a Modified Nominal Group Approach.

The Medical journal of Australia·2026
Same author

Through-Plane Conductive Hydrophobic Electrodes for CO<sub>2</sub> Electrolysis to Ethylene.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Safety and tolerability of Rinvecalinase Alfa (DM199) for acute ischemic stroke (ReMEDy1).

International journal of stroke : official journal of the International Stroke Society·2025
Same author

The virtual personality model: Toward a dynamic structured motivational systems framework for understanding personality disorders.

Journal of psychopathology and clinical science·2025
Same author

Adolescent normative beliefs about aggression mediates the association between fathers' psychological control in adolescence and physical aggression in emerging adulthood.

Social development (Oxford, England)·2025
Same author

Development of a multivariate prediction model for antidepressant resistant depression using reward-related predictors.

Frontiers in psychiatry·2024
Same journal

Hepatitis B Infection-Associated Aortoarteritis.

Annals of Indian Academy of Neurology·2026
Same journal

Correspondence- Muscle Magnetic Resonance Imaging Phenotyping and Pattern Recognition in Genetically Confirmed Myopathies: A Large-Cohort Study from the Indian Subcontinent.

Annals of Indian Academy of Neurology·2026
Same journal

STAC3-Related Congenital Myopathy (CMYP13) in an Adult Indian Patient: Expanding the Geographic Spectrum to India.

Annals of Indian Academy of Neurology·2026
Same journal

A Prospective Study on Autonomic Functions in Idiopathic Inflammatory Myopathies: The AFIIM Study.

Annals of Indian Academy of Neurology·2026
Same journal

Magnetic Resonance Imaging Findings During Encephalopathic Crisis in Glutaric Aciduria Type 1: Expanding the Radiologic Phenotype.

Annals of Indian Academy of Neurology·2026
Same journal

Thyroid Function and Cognitive Health in Older Adults: Insights from the LASI-DAD Study.

Annals of Indian Academy of Neurology·2026
See all related articles

Related Experiment Video

Updated: Jun 18, 2026

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke
06:37

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke

Published on: July 14, 2023

Early changes in physiological variables after stroke.

Andrew A Wong1, Stephen J Read

  • 1Department of Neurology, Princess Alexandra Hospital, Brisbane, Queensland, Australia. Central Clinical School, School of Medicine, University of Queensland, Brisbane, Queensland, Australia. andrewa_wong@health.qld.gov.au

Annals of Indian Academy of Neurology
|November 7, 2009
PubMed
Summary
This summary is machine-generated.

Physiological changes like blood pressure and temperature fluctuations are common after stroke. Management requires conservative measures due to unclear effects on patient prognosis.

Keywords:
Blood glucoseblood pressurebody temperaturecerebrovascular disordersoxygen

More Related Videos

Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits
05:08

Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits

Published on: March 15, 2024

Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke
09:42

Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke

Published on: September 1, 2023

Related Experiment Videos

Last Updated: Jun 18, 2026

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke
06:37

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke

Published on: July 14, 2023

Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits
05:08

Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits

Published on: March 15, 2024

Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke
09:42

Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke

Published on: September 1, 2023

Area of Science:

  • Neurology
  • Critical Care Medicine
  • Physiology

Background:

  • Physiological parameters such as blood pressure, body temperature, blood glucose, and oxygen saturation can be altered following ischemic stroke and intracerebral hemorrhage.
  • Acute post-stroke changes often include elevations in blood pressure and temperature, which typically normalize over time.
  • Blood glucose and oxygen levels exhibit variable abnormalities without a consistent pattern in stroke patients.

Purpose of the Study:

  • To investigate the determinants and prognostic implications of physiological alterations after stroke.
  • To determine whether post-stroke physiological changes are adaptive or maladaptive and subgroup-specific.
  • To clarify the impact of modifying physiological parameters on stroke outcomes.

Main Methods:

  • Review of existing literature on physiological changes post-stroke.
  • Analysis of the relationship between physiological parameters and stroke prognosis.
  • Evaluation of current management strategies and uncertainties.

Main Results:

  • The precise role of physiological changes (e.g., hypertension, hyperglycemia, hypothermia, hypoxia, hyperoxia) in stroke prognosis remains unclear.
  • The therapeutic benefits or harms of interventions targeting these physiological parameters are variable and context-dependent.
  • Stroke unit care is associated with improved outcomes, potentially due to optimized physiological management.

Conclusions:

  • Conservative management of post-stroke physiology is generally recommended, with specific exceptions for thrombolysis-eligible patients.
  • Further research is needed to elucidate the complex interactions between physiology and prognosis after stroke.
  • Stroke units play a crucial role in advancing research and refining clinical guidelines for physiological management.