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Updated: Jun 18, 2026

Drug Treatment and In Vivo Imaging of Osteoblast-Osteoclast Interactions in a Medaka Fish Osteoporosis Model
Published on: January 1, 2017
Safety and antisorptive power of Ibandronate applied in the real-life setting
Narong Bunyaratavej1, Wiwat Wajanavisit, Prayook Pauvilai
1Department of Orthopedic Surgery, Siriraj Hospital, Bangkok, Thailand. todrnarong@yahoo.com
Abstract:
This study involved 78 participants taking 150 mg of Ibandronate once a month for the investigation of the drug efficacy and safety. Ibandronate had a strong antiresorptive action that decreased 67.9 per cent of bone resorption. The total cases of unwanted effect were 21 that showed the common adverse events like other bisphosphonate. The most common events were flu-like symptom (8.75%) and dyspepsia (7.5%) which occurred at the first tablet. Most participants subsided after the following months, but only one case persisted in these symptoms through the study period while the others had a myalgia, diarrhea and burning of epigastric in percent of 6.25, 2.5, 1.25 respectively. Ibandronate (150 mg) showed the strong antiresorptive effect and good compliance for taking once a month.
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