[A case of laryngeal adenosquamous carcinoma]

We report a rare case of adenosquamous carcinoma of the larynx. A 38-year-old man with a 9-month history of progressive hoarseness and dyspnea during exercise and sudden-onset breathing difficulty was unable to be intubated and underwent a tracheostomy at the emergency department. He was found in endoscopic examination of the larynx to have a large smooth subglottic mass with laryngeal stenosis. The bilateral vocal cords were fixed. No cervical lymph node was seen. Excisional laryngofissure biopsy led to a pathological diagnosis of adenosquamous carcinoma, necessitating laryngectomy with bilateral neck dissection (Level II-IV) and postoperative radiation therapy. He died of metastatic disease 7.5 years after the initial treatment, without locoregional recurrence. Among malignant laryngeal tumors, adenosquamous carcinoma is extremely rare, with only 33 such cases including ours reported in the literature.