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Updated: Jun 18, 2026

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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Extended in vivo anterior eye-segment imaging with full-range complex spectral domain optical coherence tomography
Journal of Biomedical Optics
|November 10, 2009
Abstract:
We demonstrate the capability of full-range complex (FRC) spectral domain optical coherence tomography (SD-OCT) to image the anterior eye segment from the cornea to the posterior surface of the lens. With an adapted spectrometer design, we developed a SD-OCT system with an extended normal (single half-space) depth range of 7 mm (in air). This OCT-intrinsic depth range was doubled with a FRC technique. We demonstrate the performance of our OCT system by imaging the whole anterior segment of a healthy human eye in vivo.

