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Updated: Jun 18, 2026

Infinium Assay for Large-scale SNP Genotyping Applications

Infinium Assay for Large-scale SNP Genotyping Applications

Published on: November 19, 2013

Genome-wide association studies: a primer.

A Corvin¹, N Craddock, P F Sullivan

¹Department of Psychiatry, Trinity College Dublin, Dublin, Ireland.

Psychological Medicine

|November 10, 2009

Summary

Genome-wide association studies (GWAS) have identified genetic variants for complex diseases. This primer offers an annotated overview of GWAS methodology, focusing on psychiatric genetics and its components.

Area of Science:

Genetics
Psychiatric Genetics
Bioinformatics

Background:

Genome-Wide Association Studies (GWAS) have become a powerful tool since 2005.
Over 400 GWAS have successfully identified common genetic variants linked to complex diseases and traits.
Existing reviews cover various GWAS aspects, necessitating a focused primer.

Purpose of the Study:

To provide a primer and annotated overview of the GWAS methodology.
To specifically address the application of GWAS in psychiatric genetics.
To dissect GWAS methodology into its core components.

Main Methods:

Review and synthesis of existing GWAS literature.
Annotated overview of GWAS components.
Focus on psychiatric genetics applications.

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Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA)

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA)

Published on: August 21, 2016

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Last Updated: Jun 18, 2026

Infinium Assay for Large-scale SNP Genotyping Applications

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Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization

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Published on: July 27, 2021

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA)

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA)

Published on: August 21, 2016

Main Results:

Identification of common genetic variants for complex diseases and traits.
Detailed dissection of GWAS methodology.
Provision of citations and links for further reading.

Conclusions:

GWAS is a successful approach for identifying genetic predispositions.
This primer serves as a foundational resource for understanding GWAS, particularly in psychiatric genetics.
The overview facilitates deeper exploration of specific GWAS components and related research.