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A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis

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Published on: May 10, 2022

Validation of a simplified anorexia questionnaire.

Mellar P Davis¹, Tugba Yavuzsen, Jordanka Kirkova

¹The Harry R. Horvitz Center for Palliative Medicine, Taussig Cancer Institute, The Cleveland Clinic, Cleveland, Ohio, USA. mdavis6@ccf.org

Journal of Pain and Symptom Management

|November 10, 2009

Summary

A simplified two-item questionnaire shows moderate agreement with a longer tool for assessing cancer anorexia but lacks sensitivity over time and prognostic accuracy. Modifying the questionnaire may improve its clinical utility.

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Area of Science:

Oncology
Palliative Care
Clinical Assessment

Background:

Cancer anorexia is a common and burdensome symptom.
Current assessment tools are often lengthy and multidimensional.
Simplified questionnaires could reduce patient burden.

Purpose of the Study:

To compare the reliability, sensitivity to change, and prognostic accuracy of a two-item questionnaire against the Functional Assessment of Anorexia and Cachexia Therapy (A/CS-12).

Main Methods:

117 cancer patients completed both questionnaires at baseline and 7 days later.
Assessed one-time agreement and change over time between the two-item and A/CS-12 questionnaires.
Utilized Kaplan-Meier curves and Cox Proportional Hazards models to compare prognostic accuracy for survival.

Main Results:

One-time agreement between questionnaires was moderate (0.64).
Agreement decreased over the 7-day period (0.53).
The A/CS-12 significantly predicted survival, while the two-item questionnaire did not.

Conclusions:

The simplified two-item questionnaire has limitations in sensitivity and prognostic capability compared to the A/CS-12.
Modifications, such as neutral response options, may enhance the simplified questionnaire's performance.
Further research is needed to optimize brief symptom assessment tools in oncology.