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Updated: Jun 18, 2026
06:08
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
[Adrenal vein thrombosis during pregnancy]
C Schmitt1, M-P Debord, C Grange
1Service de gynécologie obstétrique, centre hospitalier Lyon Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite cedex, France.
Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction
|November 10, 2009
Summary
Pregnancy can reveal hidden blood clotting disorders like Factor V Leiden mutation. This case highlights adrenal vein thrombosis as a manifestation of this inherited thrombophilia during pregnancy.
Area of Science:
- Obstetrics and Gynecology
- Hematology
- Genetics
Background:
- Pregnancy is a natural prothrombotic state, increasing the risk of coagulation abnormalities.
- Inherited thrombophilias, such as Factor V Leiden mutation, are significant risk factors for venous thromboembolism.
Observation:
- A case is presented where Factor V Leiden mutation was identified during pregnancy.
- The mutation manifested as an adrenal vein thrombosis, a rare but serious complication.
Findings:
- Factor V Leiden mutation, the most common inherited thrombophilia, can be unmasked by the physiological changes of pregnancy.
- Adrenal vein thrombosis can be a presenting symptom of Factor V Leiden mutation in pregnant individuals.
Implications:
- This case underscores the importance of considering inherited thrombophilias in pregnant patients with unexplained thrombosis.
- Understanding the physiopathology of activated protein C resistance is crucial for managing thrombotic risks in pregnancy.
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