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Related Experiment Videos

Improved endocervical sampling with the Cytobrush.

A Chalvardjian1, W G De Marchi, V Bell

  • 1Department of Pathology, St. Michael's Hospital, Toronto, Ont.

CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
|February 1, 1991
PubMed
Summary
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The Zelsmyr Cytobrush is superior for collecting endocervical cells compared to the Ayre wooden spatula or cotton-tipped swab. It significantly increases cell yield and cluster size for Papanicolaou smears.

Area of Science:

  • Gynecologic pathology
  • Cervical cytology screening

Background:

  • Endocervical cell collection is crucial for accurate Papanicolaou (Pap) smear interpretation.
  • Various sampling devices exist, each with potential differences in efficacy.

Purpose of the Study:

  • To compare the effectiveness of the Ayre wooden spatula, cotton-tipped swab, and Zelsmyr Cytobrush in obtaining endocervical cells.

Main Methods:

  • A cross-sectional study was conducted in a family practice setting.
  • Three devices (spatula, swab, Cytobrush) were used randomly in each postpubertal, nonpregnant woman undergoing a Pap smear.
  • Slides were evaluated for epithelial cellularity, density, and cell cluster size by a blinded cytotechnologist.

Main Results:

Related Experiment Videos

  • The Cytobrush yielded significantly more endocervical cells (10% with no cells) compared to the spatula (57%) and swab (53%).
  • Cytobrush and spatula showed greater overall cellularity than the swab.
  • The Cytobrush produced significantly larger and more numerous cell clusters.

    • Conclusions:

    • The Zelsmyr Cytobrush is recommended for collecting endocervical cells.
    • Using the Cytobrush, alone or with the spatula, is superior to using the spatula alone or with the swab.