Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genetic variation associated with cardiovascular risk in autoimmune diseases.

PloS one·2017
Same author

Cardiovascular disease in immune-mediated inflammatory diseases: A cross-sectional analysis of 6 cohorts.

Medicine·2017
Same author

[Aldosterone/renin ratio in the diagnosis of primary aldosteronism].

Medicina·2011
Same author

Monitoring of beet armyworm resistance to spinosad and methoxyfenozide in Mexico.

Pest management science·2008
Same journal

Detection of VIM-3 in oral squamous cell carcinomas: methodological limitations.

Medicina·2026
Same journal

The importance of specific antibodies in VIM-3 research: addressing a key methodological flaw.

Medicina·2026
Same journal

[From the right to be cared for to the duty to care: Legal bases for the implementation of palliative care in Argentina].

Medicina·2026
Same journal

[Surrogacy].

Medicina·2026
Same journal

[The misunderstandings in interpreting the "diagnostic superiority of Artificial Intelligence" and the explainable Artificial Intelligence].

Medicina·2026
Same journal

[Artificial intelligence in medicine: between algorithmic opacity and clinical responsibility].

Medicina·2026
See all related articles

Related Experiment Video

Updated: Jun 18, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

[Pyogenic vertebral osteomyelitis].

Pedro P Perrotti1, José L Corrales, Bogdan M Popescu

  • 1Departamento de Medicina, Hospital Escuela José Francisco de San Martín, Facultad de Medicina, Universidad Nacional del Nordeste. pepaperrotti@hotmail.com

Medicina
|November 10, 2009
PubMed
Summary
This summary is machine-generated.

Pyogenic vertebral osteomyelitis is rare but challenging to diagnose. Early recognition of spinal infection symptoms like back pain and neurological deficits is crucial for timely treatment and recovery.

Related Experiment Videos

Last Updated: Jun 18, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

Area of Science:

  • Infectious Diseases
  • Orthopedic Surgery
  • Radiology

Background:

  • Pyogenic osteomyelitis rarely affects the spine, accounting for only 2-7% of cases.
  • Diagnosis typically relies on isolating bacterial agents from the vertebral body, intervertebral discs, or associated abscesses.

Observation:

  • This retrospective study reviewed ten patients with spinal osteomyelitis, highlighting its unusual presentations and diagnostic difficulties.
  • The lumbar and dorsal spine were most frequently affected, with dorsolumbar pain and paraparesis as common symptoms.
  • Magnetic resonance imaging (MRI) revealed typical signs of pyogenic vertebral osteomyelitis in all patients.

Findings:

  • Staphylococcus aureus was the most common pathogen (80%), followed by Escherichia coli and Haemophilus sp.
  • Leukocytosis and elevated erythrocyte sedimentation rates were infrequent, complicating early diagnosis.
  • Paravertebral and epidural abscesses were significant complications in 50% of patients.

Implications:

  • Pyogenic vertebral osteomyelitis should be considered in patients presenting with dorsolumbar pain and neurological symptoms.
  • Prompt diagnosis and treatment, including antibiotics and potentially surgery for complications, are essential for favorable outcomes.
  • This study underscores the importance of considering spinal infection in differential diagnoses for patients with suggestive symptoms.