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Related Concept Videos

Overview of the Skull01:08

Overview of the Skull

The cranium (skull) is the skeletal structure of the head that supports the face and protects the brain. It is subdivided into the facial bones and the brain case, or cranial vault. The facial bones underlie the facial structures, form the nasal cavity, enclose the eyeballs, and support the teeth of the upper and lower jaws.
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
Muscles for Facial Expressions01:14

Muscles for Facial Expressions

The craniofacial muscles are a collection of approximately 20 thin skeletal muscles situated beneath the skin of the face and scalp. These muscles, primarily responsible for the vast array of human facial expressions, originate from the bones or fibrous structures of the skull and extend outwards to connect with the skin. While most skeletal muscles in the body are enveloped in thick fascia, facial muscles generally have a more delicate fascial covering, with the buccinator muscle being a...
Cranial Bones: Lateral View01:27

Cranial Bones: Lateral View

The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Cranial Bones: Superior and Posterior View01:14

Cranial Bones: Superior and Posterior View

The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Sutures of the Skull01:22

Sutures of the Skull

The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...

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Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation
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Engineering craniofacial structures: facing the challenge.

S H Zaky1, R Cancedda

  • 1Istituto Nazionale per la Ricerca sul Cancro, and Dipartimento di Oncologia, Biologia e Genetica dell'Universita' di Genova, Largo R. Benzi, 10, 16132 Genova, Italy.

Journal of Dental Research
|November 10, 2009
PubMed
Summary
This summary is machine-generated.

Tissue engineering offers new hope for repairing irreparable craniofacial damage. This review explores strategies for regenerating bone, cartilage, and teeth using cells, scaffolds, and growth factors.

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Assessing Signaling Properties of Ectodermal Epithelia During Craniofacial Development
09:25

Assessing Signaling Properties of Ectodermal Epithelia During Craniofacial Development

Published on: March 24, 2011

Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Craniofacial Surgery

Background:

  • Human regenerative capacity is limited by injury severity and progenitor cell availability.
  • Tissue engineering emerges as a solution for reconstructing irreversibly damaged body structures.
  • Craniofacial reconstruction presents unique challenges due to complex anatomy.

Purpose of the Study:

  • To review recent advancements in engineering human craniofacial tissues, including bone, cartilage, and teeth.
  • To analyze the strategies employed in craniofacial tissue engineering.
  • To discuss the role of cell types, scaffolds, and growth factors in these strategies.

Main Methods:

  • Review of current literature on craniofacial tissue engineering trials.
  • Analysis of cell sourcing and selection for specific tissue regeneration.
  • Evaluation of scaffold design and integration for craniofacial applications.
  • Assessment of growth factor requirements for tissue development.

Main Results:

  • Recent trials focus on engineering craniofacial bone, cartilage, and teeth.
  • Successful strategies involve specific cell types, tailored scaffolds, and essential growth factors.
  • The combination of cells, scaffolds, and growth factors is crucial for targeted tissue regeneration.
  • Engineering of facial skeletal structures shows promising but challenging outcomes.

Conclusions:

  • Tissue engineering holds significant potential for treating irreparable craniofacial damage.
  • Careful selection of cells, scaffolds, and growth factors is vital for successful craniofacial regeneration.
  • Future research should address the challenges in facial skeletal engineering for improved clinical treatments.