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Japanese macaques as laboratory animals.

Tadashi Isa1, Itaru Yamane, Miya Hamai

  • 1Section for NBR Promotion, National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan.

Experimental Animals
|November 10, 2009
PubMed
Summary

The Japanese macaque (Macaca fuscata) is a valuable laboratory animal for neuroscience research due to its intelligence and gentle nature. A national project is underway to ensure a stable supply for future studies on higher cognitive functions.

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Area of Science:

  • Neuroscience
  • Primatology
  • Animal Models

Background:

  • Japanese macaques (Macaca fuscata) are favored laboratory animals in Japan.
  • Their intelligence, gentle disposition, homogeneous genetics, and well-documented social behavior make them ideal.
  • Increasing focus on higher cognitive functions in neuroscience research enhances their value.

Purpose of the Study:

  • To highlight the Japanese macaque's suitability for advanced neuroscience research.
  • To inform about the National BioResource Project (NBRP) for Japanese macaques.
  • To emphasize the future importance of this species as a laboratory model.

Main Methods:

  • Review of existing research on Japanese macaque characteristics.
  • Description of the ongoing National BioResource Project (NBRP).

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  • Discussion of the species' relevance to future neuroscience research directions.

    • Main Results:

    • Japanese macaques possess key attributes (intelligence, genetics, behavior) for neuroscience.
    • The NBRP aims to establish a stable breeding and supply system.
    • A National Primate Center is planned to support monkey supply and welfare.

    Conclusions:

    • The Japanese macaque is poised to become an increasingly important model organism in neuroscience.
    • The NBRP is crucial for ensuring the availability and ethical use of these animals.
    • Continued research and resource development will facilitate studies on complex cognitive functions.