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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Pediatric psoriasis: an update

Nanette B Silverberg1

  • 1Pediatric and Adolescent Dermatology, St. Luke's-Roosevelt Hospital Center, New York, NY, USA.

Therapeutics and Clinical Risk Management
|November 10, 2009
PubMed

Insights

Pediatric psoriasis affects children under 18, often triggered by infections. Treatment varies by severity and joint involvement, prioritizing topical therapies and considering psychological impact.

Area of Science:

  • Dermatology
  • Pediatrics
  • Immunology

Background:

  • Pediatric psoriasis accounts for approximately 25% of all psoriasis cases.
  • It manifests in various forms, including plaque, guttate, and erythrodermic types, and can be associated with psoriatic arthritis.
  • Genetic predisposition combined with environmental factors, such as upper respiratory infections, triggers disease onset.

Purpose of the Study:

  • To review current understanding of pediatric psoriasis.
  • To outline a rational therapeutic approach for managing childhood psoriasis.

Main Methods:

  • Review of existing literature on pediatric psoriasis.
  • Analysis of therapeutic strategies based on disease severity and joint involvement.

Main Results:

  • Topical treatments like corticosteroids and calcipotriene are primary initial therapies.
  • Systemic treatments including ultraviolet light, acitretin, cyclosporine, methotrexate, and etanercept are used for more severe or complex cases.
  • Methotrexate and etanercept are effective for both skin and joint manifestations.

Conclusions:

  • Treatment selection requires careful consideration of disease severity, joint involvement, and the psychological well-being of the child.
  • A multi-faceted approach is necessary for effective pediatric psoriasis management.

Keywords:
Streptococcusautoimmunitycalcipotrieneetanerceptpsoriasistopical corticosteroids

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