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Two-step LASIK after penetrating keratoplasty
Aris N Kollias1, Markus M Schaumberger, Thomas C Kreutzer
1University Eye Hospital, Ludwig-Maximilians University, Munich, Germany.
Clinical Ophthalmology (Auckland, N.Z.)
|November 10, 2009
Summary
This study shows that a two-step laser in situ keratomileusis (LASIK) approach improves refractive outcomes in patients who have undergone penetrating keratoplasty, enhancing visual acuity.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Refractive Surgery
Background:
- Penetrating keratoplasty (PK) is a corneal transplant procedure.
- Refractive errors can persist or develop after PK, necessitating further visual correction.
- Laser in situ keratomileusis (LASIK) offers a potential solution for refractive errors post-PK.
Purpose of the Study:
- To evaluate refractive changes following lamellar keratotomy (LK).
- To assess the refractive outcome of a two-step LASIK procedure in patients with prior PK.
- To determine the efficacy of LK followed by laser ablation for visual correction post-PK.
Main Methods:
- Retrospective review of eight patients who underwent a two-step LASIK procedure after PK.
- Keratotomies performed using Moria LSK one and Amadeus 2 microkeratomes.
- Laser ablation performed using Schwind Keratome I and Wavelight Allegretto WaveEyeQ excimer lasers.
Main Results:
- Significant improvement in uncorrected visual acuity (UCVA) from 1.0 to 0.4 logMar.
- Median UCVA gain of 7.38 lines; best spectacle-corrected visual acuity remained stable.
- Spherical equivalent decreased from -4.02 D to -1.11 D; manifest astigmatism reduced from -7.27 D to -2.08 D post-LASIK.
Conclusions:
- Lamellar keratotomy induces corneal biomechanical changes.
- A two-step LASIK approach enhances refractive precision and predictability in PK patients.
- This staged procedure is favored for optimizing visual outcomes after corneal transplantation.

