Related Experiment Video
Updated: Jun 18, 2026

Quantification of Circulating Pig-Specific DNA in the Blood of a Xenotransplantation Model
Published on: September 22, 2020
Multiple Asian pig origins revealed through genomic analyses
Erin S Luetkemeier1, Monika Sodhi, Lawrence B Schook
1Department of Animal Sciences, University of Illinois, 374 Edward R. Madigan Lab, 1201 West Gregory Drive, Urbana, IL 61801, USA.
European and Asian pigs have distinct origins. European domestic pigs stem from a single ancestral lineage, while Asian pigs show multiple ancestral origins, confirmed by microsatellite and mtDNA analyses.
Area of Science:
- Genetics
- Animal Science
- Evolutionary Biology
Background:
- Mitochondrial DNA (mtDNA) studies suggest multiple domestication events for European and Asian pig populations.
- Investigating distinct ancestral origins within regional domestic pig populations is crucial for understanding pig domestication.
Purpose of the Study:
- To determine if domestic pig populations originated from distinct ancestors within Europe and Asia.
- To differentiate between European and Asian pig ancestries using genomic and mtDNA data.
Main Methods:
- Genomic analysis using 21 microsatellite markers (MS) across the pig genome.
- Mitochondrial DNA (mtDNA) D-loop region sequencing.
- Phylogenetic and principal component analyses.
Main Results:
- Wild boar populations exhibited higher heterozygosity than domestic breeds.
- Microsatellite and mtDNA analyses revealed distinct European and Asian pig population clusters.
- Asian populations comprised three distinct genetic groups, suggesting multiple Asian ancestral origins.
- European domestic breeds clustered tightly, indicating a single European ancestral lineage.
Conclusions:
- European domestic pig populations likely originated from a single ancestral lineage.
- Asian domestic pig populations appear to have multiple distinct ancestral origins.
- Combined microsatellite and mtDNA analyses provide robust insights into pig domestication history.
Related Concept Videos
Evolutionary Relationships through Genome Comparisons
Modern Molecular Taxonomy
Single Nucleotide Polymorphisms-SNPs
Convergent Evolution
Exon Recombination
Exon shuffling follows “splice frame rules.” Each exon has three reading...
Incomplete Dominance

