Related Experiment Video

Updated: Jun 18, 2026

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
09:02

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions

Published on: September 22, 2023

[Pathologic findings and main aetiologies of rhinosinusal infections]

Marius Ilie1, Véronique Hofman, Catherine Butori

  • 1Laboratoire de pathologie clinique et expérimentale, hôpital Pasteur, 30, avenue de la Voie-Romaine, BP 69, 06002 Nice cedex 01, France.

Annales De Pathologie
|November 11, 2009
PubMed

Insights

Infectious diseases affecting the rhinosinusal tract, including bacterial, viral, fungal, and parasitic types, can cause inflammation in any patient. Surgical pathologists analyze biopsy specimens to identify these diverse infections.

Area of Science:

  • Pathology
  • Infectious Diseases
  • Otolaryngology

Context:

  • The rhinosinusal tract is susceptible to a wide range of infectious agents.
  • Infections can manifest acutely or chronically.
  • Both immunocompetent and immunodeficient individuals can be affected.

Purpose:

  • To describe the pathological features of infectious diseases of the rhinosinusal tract.
  • To aid surgical pathologists in diagnosing these conditions from biopsy specimens.

Summary:

  • Bacterial, viral, fungal, and parasitic infections commonly involve the rhinosinusal tract, leading to inflammatory responses.
  • Clinical presentations vary, with some infections requiring urgent diagnosis and treatment.
  • This review focuses on the histopathological findings encountered in rhinosinusal biopsies.

Impact:

  • Facilitates accurate diagnosis of diverse rhinosinusal infections.
  • Supports timely and appropriate patient management.
  • Enhances understanding of the pathological spectrum of rhinosinusal diseases.

More Related Videos

Murine Nasal Lavage Fluid Collection without Blood Contamination05:12

Murine Nasal Lavage Fluid Collection without Blood Contamination

Published on: July 11, 2025

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Related Concept Videos

Anatomy of Respiratory System I: Upper Respiratory Tract01:29

Anatomy of Respiratory System I: Upper Respiratory Tract

The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.
Nose and Nasal Cavity01:24

Nose and Nasal Cavity

The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.