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Updated: Jun 18, 2026

Learning Modern Laryngeal Surgery in a Dissection Laboratory
Published on: March 18, 2020
Laser reduction glottoplasty for managing androphonia after failed cricothyroid approximation surgery
Ismail Koçak1, Meltem Esen Akpınar, Zeynep Alkan Cakır
1University Hospital, Department of Otolaryngology, Istanbul, Turkey.
Objective:
To treat androphonic voice quality after failed cricothyroid approximation (CTA) surgery.
Study Design:
Prospective case series.
Methods:
The voices of three male-to-female transsexuals, two constitutional androphonic females, and one patient with ambiguous genitalia assigned to the female phenotype were deemed to be unimproved after CTA. The patients underwent laser reduction glottoplasty (LRG) surgery tailored to each case between 2001 and 2005. Vocal outcomes were evaluated according to fundamental frequency (FF), satisfaction status, voice-related quality of life (V-RQOL) measures, and ratings of recorded voices by 10 blinded listeners after 12 months postoperatively.
Results:
The LRG provided an additional mean gain of 45.17±8.47Hz (mean±standard deviation) in the FF, equal to 4.36±0.84 semitones. The mean FF increased significantly (P<0.05) from 158.33±12.14Hz preoperatively to 203.50±13.34Hz postoperatively. All patients reported satisfactory female quality in their voices and greetings with female salutations in nonvisual communications. Their voice-related quality of life (V-RQOL) measures were high and significantly elevated (P<0.05) after LRG. The masculine voice-quality ratings significantly shifted to feminine in the listeners' assessment. No major complications were observed during follow-up, with the exception of mild vocal fold edema that disappeared by 8 weeks postoperatively.
Conclusions:
LRG can be used in androphonic cases that fail to obtain a high-pitched feminine voice after CTA.
