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Harlequin syndrome: two new cases and a management proposal
W I M Willaert1, M R M Scheltinga, S F Steenhuisen
1Department of Vascular Surgery, Máxima Medical Center, Veldhoven, The Netherlands.
Acta Neurologica Belgica
|November 12, 2009
Summary
Harlequin syndrome, a rare autonomic disorder, causes one-sided facial sweating and flushing. This study reviews 83 cases to offer diagnostic and therapeutic guidance for this condition.
Area of Science:
- Neurology
- Autonomic Nervous System Disorders
Background:
- Harlequin syndrome is an uncommon autonomic disorder.
- It manifests as unilateral facial sweating and flushing.
- Symptoms are typically triggered by heat or exercise.
Observation:
- Presents two new cases of Harlequin syndrome.
- Analyzes data from 83 previously reported patients in the literature.
- Documents the clinical presentation and progression of the disorder.
Findings:
- Confirms the characteristic unilateral thermoregulatory dysfunction.
- Identifies patterns in patient demographics and triggers.
- Highlights the diagnostic challenges and variability in presentation.
Implications:
- Provides updated diagnostic criteria for Harlequin syndrome.
- Offers evidence-based therapeutic strategies and management guidelines.
- Aims to improve clinical recognition and patient outcomes for this rare condition.
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