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Updated: Jun 18, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Migraine presenting as chronic facial pain
1Headache Clinic, Department of Neurology, University Hospital UZ Gasthuisberg, Leuven, Belgium. freddebruyne@yahoo.com
This case study highlights medication-overuse headache (MOH) in a patient with chronic facial pain. Effective treatment began after diagnosing MOH complicating migraine without aura, emphasizing atypical migraine presentations.
Area of Science:
- Neurology
- Pain Medicine
- Headache Disorders
Background:
- Migraine is a common primary headache disorder.
- Facial pain can be an atypical presentation of migraine.
- Chronic facial pain often requires differential diagnosis.
Observation:
- A 44-year-old woman presented with chronic facial pain unresponsive to various treatments.
- Initial treatments included analgesics, prophylactic medications, and infiltrations.
- The patient's symptoms were ultimately diagnosed as medication-overuse headache (MOH).
Findings:
- MOH complicated a pre-existing migraine without aura.
- Atypical migraine presentation as isolated facial pain can occur.
- Pain arises from trigeminovascular system activation, referring to trigeminal nerve divisions.
Implications:
- Accurate diagnosis of atypical migraine presentations is crucial.
- MOH requires specific management strategies.
- Understanding the neuroanatomy of migraine pain aids in diagnosis and treatment.
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