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Published on: June 15, 2019
Lethal sphenoid fungal sinusitis in an immunocompromised elderly patient
1Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, Changhua, Taiwan.
Abstract:
Sphenoid fungal balls are rare and typically indolent lesions, unless superinfected by bacteria or invasive to adjacent neurovascular structures. If the identification or treatment of underlying complications is delayed in an immunocompromised patient, a catastrophic outcome may result. We report the case of an elderly female patient with poorly controlled diabetes mellitus suffering from sphenoid fungal sinusitis that is complicated by cavernous sinus thrombophlebitis and carotid artery stenosis. In spite of reasonable diagnosis and therapy, the patient's general condition deteriorated and she eventually died. The clinical presentation, diagnosis, and treatment strategy are discussed.
Insights
Sphenoid fungal balls, though rare, can be life-threatening when complicated by infections or invasion. This case highlights the severe risks in immunocompromised patients with poorly controlled diabetes.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Neurosurgery
Background:
- Sphenoid fungal balls are uncommon sinus infections.
- They are usually slow-growing but can become invasive.
- Superinfection or invasion poses significant risks, especially in immunocompromised individuals.
Observation:
- An elderly female patient with uncontrolled diabetes presented with sphenoid fungal sinusitis.
- The condition was complicated by cavernous sinus thrombophlebitis and carotid artery stenosis.
- Despite timely diagnosis and treatment, the patient's condition worsened.
Findings:
- The case illustrates a fatal outcome from sphenoid fungal sinusitis.
- Complications included cavernous sinus thrombophlebitis and carotid artery stenosis.
- Delayed identification and treatment of complications in immunocompromised patients can be catastrophic.
Implications:
- Early recognition and aggressive management of sphenoid fungal sinusitis are crucial.
- Underlying conditions like diabetes mellitus significantly increase patient risk.
- This case underscores the importance of considering invasive fungal sinusitis in diabetic patients with neurological symptoms.
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