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[2 newborn infants with septicemia caused by multiresistant Streptococcus mitis]
1Centraal Klinisch Bacteriologisch, Academisch Ziekenhuis, Leiden.
Nederlands Tijdschrift Voor Geneeskunde
|January 12, 1991
Summary
Multiresistant viridans streptococci, including Streptococcus mitis, were identified in Dutch neonates. This finding is significant as these bacteria typically remain sensitive to penicillin and beta-lactam antibiotics.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Background:
- Viridans streptococci are typically highly susceptible to penicillin and other beta-lactam antibiotics.
- Multiresistant strains of viridans streptococci had not previously been reported in the Netherlands.
Observation:
- In the spring of 1990, multiresistant Streptococcus mitis was isolated from the blood of two neonates in the Netherlands.
- Both neonates developed septicemia while undergoing treatment with beta-lactam antibiotics.
Findings:
- The isolated Streptococcus mitis strains exhibited significant resistance to penicillin (minimal inhibitory concentration of 64 mg/l).
- This represents the first documented instance of multiresistant viridans streptococci in the Netherlands.
Implications:
- The emergence of multiresistance in typically susceptible bacteria like viridans streptococci is a growing concern.
- Clinicians should consider the potential for (multi-)resistance development in these microorganisms during antibiotic therapy.
- This case highlights the need for ongoing surveillance of antimicrobial resistance patterns in healthcare settings.