Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Personality Disorders: Dependent and Obsessive-Compulsive

Personality Disorders: Dependent and Obsessive-Compulsive

Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle with...

Horney's Sociocultural Approach

Horney's Sociocultural Approach

Karen Horney's psychoanalytic theories emphasize the potential for self-realization and the importance of addressing social and cultural, rather than biological, factors in personality development. She challenged traditional Freudian views, particularly Freud's concept of "penis envy," which she argued stemmed from cultural influences rather than inherent biological differences. Horney believed that any sense of inferiority in women was a result of societal conditioning, such as dependence on...

Personality Disorders: Narcissistic and Avoidant

Personality Disorders: Narcissistic and Avoidant

Narcissistic and avoidant personality traits represent two contrasting patterns of behavior that significantly influence social interactions and self-perception. While individuals with narcissistic disorder seek admiration and validation, individuals with avoidant personality disorder withdraw due to fear of judgment.
Characteristics of Narcissistic Personality Disorder
Narcissistic individuals exhibit an inflated sense of self-importance and an excessive need for admiration. They are often...

Anorexia Nervosa

Anorexia Nervosa

Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...

Depressive Disorders: Etiology

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Stress resilience: a predictor of social independence.

Anxiety, stress, and coping·2026

Same author

Images of social support reminders, but not learned safety signals, reduce long-term fear.

Scientific reports·2025

Same author

Social support and fear-inhibition: an examination of underlying neural mechanisms.

Social cognitive and affective neuroscience·2024

Same author

On Mounting Preparations under Thin Glass.

Medical examiner (Philadelphia, Pa.)·2023

Same author

Lipopolysaccharide structure modulates cationic biocide susceptibility and crystalline biofilm formation in <i>Proteus mirabilis</i>.

Frontiers in microbiology·2023

Same author

Investigating dysphagia in adults: symptoms and tests.

BMJ (Clinical research ed.)·2022

Search research articles

Related Experiment Video

Updated: Jun 18, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Neuroticism as a common dimension in the internalizing disorders.

J W Griffith¹, R E Zinbarg, M G Craske

¹Department of Psychology, Northwestern University, Chicago, IL, USA. jameswgriffith@gmail.com

Psychological Medicine

|November 12, 2009

Summary

This summary is machine-generated.

Neuroticism is strongly linked to an internalizing factor common in mood and anxiety disorders. This suggests neuroticism may be the core of internalizing psychopathology in adolescents.

More Related Videos

Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling

Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling

Published on: January 17, 2025

Related Experiment Videos

Last Updated: Jun 18, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling

Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling

Published on: January 17, 2025

Area of Science:

Psychiatry
Clinical Psychology
Developmental Psychology

Background:

Mood and anxiety disorders frequently co-occur, suggesting shared underlying factors.
Personality traits, particularly neuroticism, are hypothesized to explain this comorbidity.
Previous research indicates a potential link between neuroticism and internalizing dimensions.

Purpose of the Study:

To investigate the relationship between neuroticism and a common internalizing factor in mood and anxiety disorders.
To determine if neuroticism is a core component of internalizing psychopathology.
To assess the convergent and discriminant validity of neuroticism in relation to internalizing and substance use factors.

Main Methods:

A diverse adolescent sample (n=621) was assessed using self-report and peer-report measures of neuroticism.
Participants underwent the Structured Clinical Interview for DSM-IV (SCID) for diagnostic assessment.
Structural equation modeling was employed to analyze the relationships between variables.

Main Results:

A single internalizing factor significantly correlated with lifetime diagnoses of mood and anxiety disorders.
Neuroticism demonstrated a strong correlation (r=0.98) with this internalizing factor.
Neuroticism showed higher correlation with the internalizing factor compared to a substance use factor (r=0.29), supporting its validity.

Conclusions:

Neuroticism is a significant factor in the etiology and structure of mood and anxiety disorders.
The findings suggest neuroticism may represent the core of internalizing psychopathology.
Further research is recommended to confirm these findings in diverse populations.