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Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Pleuropulmonary blastoma in an infant
Yi Cheng Shi1, Lan Fang Tang, Zhi Min Chen
1Department of Pulmonology, the Children's Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Indian Journal of Pediatrics
|November 12, 2009
Summary
This report details a rare infantile case of type III pleuropulmonary blastoma (PPB), a highly aggressive tumor. Successful surgical resection and positive patient outcome highlight effective management strategies for this pediatric malignancy.
Area of Science:
- Pediatric Oncology
- Thoracic Surgery
- Pathology
Background:
- Pleuropulmonary blastomas (PPB) are rare, aggressive pediatric lung neoplasms.
- Type III PPB presents as a cystic and solid mass, often with associated lung changes.
Observation:
- A 9-month-old boy presented with cough and tachypnea.
- Chest CT revealed a left upper lobe mass, emphysema, and mediastinal shift.
- Surgical resection via left upper lobectomy was performed.
Findings:
- Histopathology confirmed type III pleuropulmonary blastoma.
- Immunohistochemistry showed vimentin positivity in blastematous tissue and EMA/cytokeratin in benign epithelium.
- No lymph node metastasis was identified in examined hilar lymph nodes.
Implications:
- Complete surgical resection is crucial for managing type III PPB.
- Early diagnosis and prompt surgical intervention can lead to favorable outcomes.
- This case contributes to understanding the clinical and pathological spectrum of infantile PPB.
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