Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Drug Dosing: Geriatric Patients

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

Nursing Assessment of the Genitourinary System I: Health History

Nursing Assessment of the Genitourinary System I: Health History

The genitourinary system is critical to maintaining fluid balance, waste elimination, and reproductive function. Nurses play a vital role in assessing this system, beginning with a thorough health history. This process involves gathering patient information, identifying risk factors, and recognizing symptoms of genitourinary disorders. Early detection is vital for timely interventions and management.1. Gathering Patient InformationA complete health history includes the patient’s personal,...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...

Urinary Bladder

Urinary Bladder

The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...

Pharmacodynamics in Geriatric Patients: Effects of Age

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[A QUESTIONNAIRE SURVEYON TREATMENT SELECTION FOR PATIENTS WITH ADVANCED PROSTATE CANCER IN JAPAN].

Hinyokika kiyo. Acta urologica Japonica·2026

Same author

Vapor-Controlled Full-Color Luminescence in Platinum(II) Complexes Bearing N-Heterocyclic Carbene and a Flexible Alkyl Chain.

Angewandte Chemie (International ed. in English)·2026

Same author

Switchable photoluminescence of europium(III) complexes with chromonylhydrazones.

Chemical communications (Cambridge, England)·2026

Same author

Clinical utility of urinary microRNA (miR-1273g-3p) in male patients with detrusor underactivity.

World journal of urology·2026

Same author

Genetic Predictors of Progression and Skin Rash in Japanese mCSPC Patients Treated With Apalutamide: CUARTET Study.

Cancer science·2026

Same author

Efficacy and Safety of Vibegron Add-On Therapy for Persistent Overactive Bladder Symptoms in Benign Prostatic Hyperplasia Patients With α<sub>1</sub>-Blocker Treatment: A Multi-Center Prospective Randomized Controlled Study (VATON Study).

Lower urinary tract symptoms·2026

Search research articles

Related Experiment Video

Updated: Jun 18, 2026

Real-Time Void Spot Assay

Real-Time Void Spot Assay

Published on: February 10, 2023

Perspectives on overactive bladder in the elderly population.

Masaki Yoshida¹

¹Department of Urology, Kumamoto Hospital of Japan Labor Health and Welfare Organization, 3-30-34-1402 Suizenji, Kumamoto, 862-0950, Japan. akko-maki@umin.net

World Journal of Urology

|November 12, 2009

Summary

This summary is machine-generated.

Overactive bladder (OAB) management in the elderly requires careful consideration of multiple health conditions. Healthcare professionals need increased awareness to provide optimal care for this growing patient population.

More Related Videos

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Related Experiment Videos

Last Updated: Jun 18, 2026

Real-Time Void Spot Assay

Real-Time Void Spot Assay

Published on: February 10, 2023

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Area of Science:

Geriatric Medicine
Urology
Pharmacology

Background:

Overactive bladder (OAB) significantly impacts lower urinary tract storage function, disproportionately affecting the elderly.
Anticipated global population aging suggests a rising healthcare burden from OAB.
OAB pathophysiology in older adults is multifactorial, involving neural, urothelial, and detrusor muscle abnormalities leading to urgency and involuntary contractions.

Purpose of the Study:

To review key management aspects of overactive bladder in the elderly population.
To address the growing healthcare needs associated with OAB in aging demographics.

Main Methods:

A literature review focusing on overactive bladder management strategies in elderly patients.
Analysis of OAB pathophysiology and treatment considerations in a geriatric context.

Main Results:

Elderly patients often present with comorbidities, necessitating comprehensive health assessments for OAB management.
Lifestyle interventions and pharmacotherapy are effective for OAB in the elderly.
Non-urology specialists frequently manage OAB in this population due to complex health profiles.

Conclusions:

Increased awareness of OAB and its impact among healthcare professionals is crucial.
Tailored care approaches are essential for effectively managing OAB in the elderly, considering their unique health circumstances.