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Related Concept Videos

Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

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Related Experiment Video

Updated: Jun 18, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
09:48

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

Endometrial cancer.

Edward M Buchanan1, Lara Carson Weinstein, Christina Hillson

  • 1Department of Family and Community Medicine, Thomas Jefferson University, Philadelphia, PA, USA. Edward.Buchanan@jefferson.edu

American Family Physician
|November 13, 2009
PubMed
Summary
This summary is machine-generated.

Endometrial cancer, a common gynecologic malignancy, is often linked to estrogen. Diagnosis involves various methods, with definitive confirmation requiring pathology, and treatment depends on surgical staging.

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Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
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Quantitation of Intra-peritoneal Ovarian Cancer Metastasis

Published on: July 18, 2016

Related Experiment Videos

Last Updated: Jun 18, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
09:48

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
10:58

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis

Published on: July 18, 2016

Area of Science:

  • Gynecologic Oncology
  • Reproductive Endocrinology

Background:

  • Endometrial cancer is the most common gynecologic cancer in the U.S.
  • Typically arises from unopposed estrogen stimulation, but non-estrogen-dependent forms exist.
  • Postmenopausal bleeding is the most frequent presenting symptom.

Purpose of the Study:

  • To review the etiology, diagnosis, and management of endometrial cancer.
  • To highlight the importance of diagnostic modalities and surgical staging.

Main Methods:

  • Review of diagnostic modalities including endometrial biopsy, ultrasonography, saline infusion sonography, and hysteroscopy.
  • Pathologic confirmation via endometrial biopsy or dilatation and curettage.
  • Surgical staging to guide treatment decisions.

Main Results:

  • Definitive diagnosis relies on histopathologic examination.
  • Treatment strategies, including surgery, radiation, and chemotherapy, are determined by tumor stage and grade.
  • No general population screening recommendations are currently available.

Conclusions:

  • Endometrial cancer management is multifaceted, involving accurate diagnosis and tailored treatment based on staging.
  • Early detection and appropriate intervention are crucial for patient outcomes.